Chemotherapy-Induced Neuropathic Pain.pdf

Chemotherapy-Induced Neuropathic Pain PDF

There have been tremendous recent advances in the pharmacotherapy, dose regimens, and combinations used to treat cancer and for the treatment or prevention of the spread of disease. As a direct result of these advances, there are an increasing number of cancer survivors, although research dealing with chemotherapy-induced pain is still in its early years. Written for pain management specialists, oncologists, pharmacologists, students, and primary care practitioners, Chemotherapy-Induced Neuropathic Pain provides insight into the important area of chemotherapy-induced neuropathic pain. It reviews the basic and clinical research into the normal physiology of pain transmission pathways, neuropathic pain pathology, the chemotherapeutic drug mechanisms of action and adverse effects, chemotherapy-induced neuropathy, and drug discovery efforts for treatment. The contributors comprise an impressive list of clinical and basic science experts in the fields of pain mechanisms and pain management. Included are clinical directors of pain clinics and clinical research facilities, directors of large academic pain research laboratories, analgesic drug developers, and presidents of the International Association for the Study of Pain (IASP), Association of Chronic Pain Patients (ACPP), and the British Pain Society (BPS). Through them, the book provides the reader with an exceptional opportunity to acquire a fundamental understanding of the basic concepts related to this topic.

Pain in chemotherapy-induced peripheral … 19.10.2018 · The quality of neuropathic pain in CINP is often described by qualifiers such as shooting and/or burning, and such pain qualities are reported in approximately 40% of patients with CIPN [9]. It is known that Vinca alkaloids and platinum salts have toxic effects on the DRG neurons, and increase the activity the voltage-dependent sodium channels [10-11]. This …

1.77 MB DATEIGRÖSSE
9781439862193 ISBN
Englisch SPRACHE
Chemotherapy-Induced Neuropathic Pain.pdf

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Sofia Voigt

Chemotherapy‐Induced Neuropathic Pain and Its …

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Matteo Müller

Purpose of review To discuss the importance, clinical features, possible pathology and treatments of chemotherapy-induced neuropathic pain. Newer biological agents such as bortezomib will be considered in greater detail.. Recent findings Chemotherapy-induced peripheral neuropathy (CIPN) is a frequent complication of common anticancer therapies. It may lead to treatment …

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Noel Schulze

Introduction. Several lines of evidence have shown that 25% to 50% of patients treated with chemotherapeutic agents, mainly from the taxane, vinca alkaloid and platinum classes, develop peripheral neuropathy that may be accompanied with neuropathic pain (NP) syndrome. 1-3 This adverse effect is usually manifested as sensory dysfunction and severe pain. 4-7 Notably, once chemotherapy‐induced … Chemotherapy-induced neuropathic pain | …

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Jason Lehmann

11 Mar 2020 ... Chemotherapy-induced peripheral neuropathy (CIPN) is a common cause of pain and poor quality of life for those undergoing treatment for ...

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Jessica Kohmann

28 Aug 2019 ... Animals and chemotherapy-induced peripheral neuropathic pain model. Tlr9 mutant mice (C57BL/6J-Tlr9M7Btlr/Mmjax, stock #34329) and WT ... Chemotherapy-induced peripheral neuropathy. Curr Pain Headache Rep, 12 ( 2008), pp. 165-174. Medline. [7.] S.M. Swain, J.C. Arezzo. Neuropathy associated  ...