Cells, Aging, and Human Disease.pdf

Cells, Aging, and Human Disease PDF

Michael B. M. D. Fossel

Cells, Aging, and Human Disease is the first book to explore aging all the way from genes to clinical application, analyzing the fundamental cellular changes which underlie human age-related disease. With over 4,000 references, this text explores both the fundamental processes of human aging and the tissue-by-tissue pathology, detailing both breaking research and current state-of-the-art clinical interventions in aging and age-related disease.

Far from merely sharing a common onset late in the lifespan, age-related diseases are linked by fundamental common characteristics at the genetic and cellular levels. Emphasizing human cell mechanisms, the first section presents and analyzes our current knowledege of telomere biology and cell senescence. In superb academic detail, the text brings the reader up to date on telomere maintenance, telomerase dynamics, and current research on cell senescence--and the general model--cell senescence as the central component in human senescence and cancer. For each human malignancy, the chapter reviews and analyzes all available data on telomeres and telomerase, as well as summarizing current work on their clinical application in both diagnosis and cancer therapy.

The second edition, oriented by organs and tissues, explores the actual physiological impact of cell senescence and aging on clinical disease. After a summary of the literature on early aging syndromes--the progerias--the text reviews aging diseases (Alzheimers dementia, osteoarthritis, atherosclerosis, immune aging, presbyopia, sarcopenia, etc.) in the context of the tissues in which they occur. Each of the ten clinical chapters--skin, cardiovascular system, bone and joints, hematopoetic and immune systems, endocrine, CNS, renal, muscle, GI, and eyes--examines what we know of their pathology, the role of cell sensescence, and medical interventions, both current and potential.

01.08.2005 · Telomere length and telomerase activity are important factors in the pathobiology of human disease. Age-related diseases and premature ageing syndromes are characterized by short telomeres, which

3.22 MB DATEIGRÖSSE
0198032196 ISBN
Englisch SPRACHE
Cells, Aging, and Human Disease.pdf

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Sofia Voigt

Buy Cells, Aging, and Human Disease by Michael Fossel (ISBN: 9780195140354) from Amazon's Book Store. Everyday low prices and free delivery on eligible orders. Cells Aging And Human Disease PDF EPUB …

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Download Cells Aging And Human Disease in PDF and EPUB Formats for free. Cells Aging And Human Disease Book also available for Read Online, mobi, docx and mobile and kindle reading. Human aging and disease - ScienceDirect

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Noel Schulze

Download [PDF] Cells Aging And Human Disease … Cells, Aging, and Human Disease is the first book to explore aging all the way from genes to clinical application, analyzing the fundamental cellular changes which underlie human age-related disease. With over 4,000 references, this text explores both the fundamental processes of human aging and the tissue-by-tissue pathology, detailing both

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Jason Lehmann

Aging changes in organs, tissues, and cells All vital organs begin to lose some function as you age during adulthood. Aging changes occur in all of the body's cells, tissues, and organs, and these changes affect the functioning of all body systems. Aging and disease

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Jessica Kohmann

Cells, Aging, and Human Disease - Kindle edition by Michael B. M.D. Fossel. Download it once and read it on your Kindle device, PC, phones or tablets. Use features like bookmarks, note taking and highlighting while reading Cells, Aging, and Human Disease.